{"product_id":"book-3d-2026-common-terminology-criteria-for-adverse-events-ctcae","title":"Book 3D v5.0:  Version 5.0 Common Terminology Criteria for Adverse Events (CTCAE)","description":"\u003cdiv id=\"tabs\"\u003e\n\u003cul\u003e\n\u003cli\u003e\u003ca href=\"#tabs-1\"\u003eDescription\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"#tabs-2\"\u003eContents\u003c\/a\u003e\u003c\/li\u003e\n\u003cli\u003e\u003ca href=\"#tabs-3\"\u003eCover\u003c\/a\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cdiv id=\"tabs-1\"\u003e\n\u003cp align=\"left\" class=\"bigblacktext\"\u003e\u003cspan class=\"smallgray\"\u003eCTCAE is a list of adverse event (AE) terms commonly encountered in oncology. Each AE term is defined and accompanied by a grading scale that indicates the severity of the AE. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"left\" class=\"bigblacktext\"\u003e\u003cspan class=\"smallgray\"\u003ePublished on November 27, 2017 CTCAE v5.0 AE terms are organized by the System Organ Classes (SOCs) defined by the Medical Dictionary for Regulatory Activities (MedDRA). \u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"left\" class=\"bigblacktext\"\u003e\u003cspan class=\"smallgray\"\u003eCTCAE v6.0 was published on July 22, 2025.  Please see the \u003cem\u003eContents\u003c\/em\u003e Tab for FAQs on versions 6.0 and 5.0. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp align=\"left\" class=\"bigblacktext\"\u003e\u003cspan color=\"#000099\" style=\"color: #000099;\"\u003eWhat's the Price?\u003c\/span\u003e\u003cbr\u003e\u003cspan class=\"smallgray\"\u003e• 1-249 copies:  $16.95             • 250-499 copies:  $15.95\u003cbr\u003e• 500-749 copies: $14.95          • 750+ copies:  $13.95\u003cbr\u003e\u003cspan color=\"#000099\" style=\"color: #000099;\"\u003e\u003cbr\u003e\u003c\/span\u003e\u003c\/span\u003e\u003cspan color=\"#000099\" style=\"color: #000099;\"\u003eCustom Cover Prices*?\u003c\/span\u003e\u003cspan class=\"smallgray\"\u003e\u003cbr\u003e• 1-24 copies:  unavailable             • 25-100 copies:  $2.00\/book\u003cbr\u003e• 100-249 copies: $1.00\/book        • 250+ copies:  No charge \u003cspan color=\"#000099\" style=\"color: #000099;\"\u003e\u003c\/span\u003e\u003cbr\u003e\u003cbr\u003e\u003cbr\u003e\u003cspan color=\"#000099\" style=\"color: #000099;\"\u003e* Based on quantities of a single book title\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv id=\"tabs-2\"\u003e\n\u003cp align=\"center\" class=\"smallblack\"\u003e\u003cspan color=\"#000000\" style=\"color: #000000;\"\u003eCommon Terminology Criteria for\u003cbr\u003eAdverse Events (CTCAE)\u003cbr\u003e\u003cspan class=\"smallgray\"\u003e\u003cstrong\u003eVersion 5.0\u003c\/strong\u003e \u003cbr\u003ePublished: November 27, 2017\u003cbr\u003eU.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES \u003cbr\u003eNational Institutes of Health \u003cbr\u003eNational Cancer Institute\u003c\/span\u003e\u003c\/span\u003e\u003cspan color=\"#000000\" style=\"color: #000000;\"\u003e\u003cbr\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp style=\"text-align: center;\" class=\"smallblack\" align=\"center\"\u003e \u003c\/p\u003e\n\u003cp style=\"text-align: center;\" class=\"smallblack\" align=\"center\"\u003e\u003cspan style=\"color: #000000;\" color=\"#000000\"\u003e\u003cspan class=\"smallgray\"\u003e\u003cstrong\u003eCTCAE \u003c\/strong\u003e\u003c\/span\u003e\u003c\/span\u003e\u003cspan color=\"#000000\" style=\"color: rgb(163, 0, 0);\"\u003e\u003cspan class=\"smallgray\"\u003e\u003cstrong\u003ev6.0\u003c\/strong\u003e\u003c\/span\u003e\u003c\/span\u003e\u003cspan style=\"color: #000000;\" color=\"#000000\"\u003e\u003cspan class=\"smallgray\"\u003e\u003cstrong\u003e Implementation FAQs\u003c\/strong\u003e\u003cbr\u003e\u003cstrong\u003eSeptember 9, 2025\u003c\/strong\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp style=\"text-align: left;\" class=\"smallblack\" align=\"center\"\u003e\u003cspan style=\"color: #000000;\" color=\"#000000\"\u003e\u003cspan class=\"smallgray\"\u003e\u003cstrong\u003e❖ General Questions:\u003c\/strong\u003e\u003cbr\u003e\u003cem\u003eWhen can CTCAE v6.0 be used?\u003c\/em\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp style=\"text-align: left; padding-left: 40px;\" class=\"smallblack\" align=\"center\"\u003e\u003cspan style=\"color: #000000;\" color=\"#000000\"\u003e\u003cspan class=\"smallgray\"\u003e• CTCAE v6.0 is ready for immediate use for any study except NCI CTEP or DCP NCORP studies.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp style=\"text-align: left; padding-left: 80px;\" class=\"smallblack\" align=\"center\"\u003e\u003cspan style=\"color: #000000;\" color=\"#000000\"\u003e\u003cspan class=\"smallgray\"\u003eo If you have questions about whether you may or may not use CTCAE v6.0, please contact your study sponsor.\u003cbr\u003e\u003cem\u003e\u003c\/em\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp style=\"text-align: left;\" class=\"smallblack\" align=\"center\"\u003e\u003cspan style=\"color: #000000;\" color=\"#000000\"\u003e\u003cspan class=\"smallgray\"\u003e\u003cem\u003eAre further changes anticipated to CTCAE v6.0?\u003c\/em\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp style=\"text-align: left; padding-left: 40px;\" class=\"smallblack\" align=\"center\"\u003e\u003cspan style=\"color: #000000;\" color=\"#000000\"\u003e\u003cspan class=\"smallgray\"\u003e• No further changes are planned. The release version is the final version of CTCAE v6.0.\u003cbr\u003e• If you have comments regarding CTCAE v6.0, please send them to NCI CTEP CTCAE Comments at: ncictcaehelp@mail.nih.gov. Comments will be discussed during the CTCAE v7.0 update.\u003cbr\u003e• CTCAE v7.0 is expected to be developed and released between 2027 and 2030.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp style=\"text-align: left;\" class=\"smallblack\" align=\"center\"\u003e\u003cspan style=\"color: #000000;\" color=\"#000000\"\u003e\u003cspan class=\"smallgray\"\u003e\u003cem\u003eHow should multiple CTCAE versions be managed if data needs to be consolidated into \u003c\/em\u003e\u003cem\u003ea single version (e.g., for regulatory reporting or aggregate analysis)?\u003c\/em\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp style=\"text-align: left; padding-left: 40px;\" class=\"smallblack\" align=\"center\"\u003e\u003cspan style=\"color: #000000;\" color=\"#000000\"\u003e\u003cspan class=\"smallgray\"\u003e• The NCI has developed a comprehensive mapping resource that aligns all term and grade combinations from CTCAE v5.0 to their corresponding terms and grades in CTCAE v6.0.\u003cbr\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp style=\"text-align: left;\" class=\"smallblack\" align=\"center\"\u003e\u003cspan style=\"color: #000000;\" color=\"#000000\"\u003e\u003cspan class=\"smallgray\"\u003e\u003cstrong\u003e❖ Specific Information for NCI CTEP\/DCP-supported Studies:\u003c\/strong\u003e\u003cbr\u003e\u003cem\u003eWill NCI CTEP\/DCP studies using CTCAE v5.0 be required to convert existing data to\u003c\/em\u003e\u003cbr\u003e\u003cem\u003ev6.0?\u003c\/em\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp style=\"text-align: left; padding-left: 40px;\" class=\"smallblack\" align=\"center\"\u003e\u003cspan style=\"color: #000000;\" color=\"#000000\"\u003e\u003cspan class=\"smallgray\"\u003e• No. Data conversion will not be required by NCI CTEP\/DCP.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp style=\"text-align: left; padding-left: 80px;\" class=\"smallblack\" align=\"center\"\u003e\u003cspan style=\"color: #000000;\" color=\"#000000\"\u003e\u003cspan class=\"smallgray\"\u003eo All NCI CTEP\/DCP studies currently reporting in CTCAE v5.0 will continue to report in CTCAE v5.0 throughout the life of the study.\u003cbr\u003eo All NCI CTEP\/DCP data reporting (CDUS, DMU, CTEP-AERS) will remain in CTCAE v5.0.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp style=\"text-align: left;\" class=\"smallblack\" align=\"center\"\u003e\u003cspan style=\"color: #000000;\" color=\"#000000\"\u003e\u003cspan class=\"smallgray\"\u003e\u003cem\u003eWhich NCI CTEP\/DCP studies will be required to use CTCAE v6.0?\u003c\/em\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp style=\"text-align: left; padding-left: 40px;\" class=\"smallblack\" align=\"center\"\u003e\u003cspan style=\"color: #000000;\" color=\"#000000\"\u003e\u003cspan class=\"smallgray\"\u003e• CTCAE v6.0 will be required for ALL NEW NCI CTEP\/DCP studies whose Rave study build begins after the CTCAE v6.0 Rave ALS (ALS 7.2) is released.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp style=\"text-align: left; padding-left: 80px;\" class=\"smallblack\" align=\"center\"\u003e\u003cspan style=\"color: #000000;\" color=\"#000000\"\u003e\u003cspan class=\"smallgray\"\u003eo This applies to all NCI CTEP and DCP studies regardless of IND status and includes nonIND and IND-Exempt studies.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp style=\"text-align: left;\" class=\"smallblack\" align=\"center\"\u003e\u003cspan style=\"color: #000000;\" color=\"#000000\"\u003e\u003cspan class=\"smallgray\"\u003e\u003cem\u003eWhen will Rave ALS 7.2 be released?\u003c\/em\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp style=\"text-align: left; padding-left: 40px;\" class=\"smallblack\" align=\"center\"\u003e\u003cspan style=\"color: #000000;\" color=\"#000000\"\u003e\u003cspan class=\"smallgray\"\u003e• The release of Rave ALS 7.2 is tentatively scheduled for July 2026.\u003cbr\u003e• The timeline may be further pushed back based on resource needs in support of other Medidata-related priorities.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv id=\"tabs-3\"\u003e\n\u003cp\u003eClick \u003ca rel=\"noopener\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0856\/8592\/files\/book3dcoiled.pdf?v=1744481185\" target=\"_blank\"\u003ehere\u003c\/a\u003e to see an enlarged pdf cover\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"Clinical Research Resources, LLC","offers":[{"title":"Default Title","offer_id":44561131536499,"sku":null,"price":16.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0856\/8592\/files\/2026book3dcoiled.png?v=1775164671","url":"https:\/\/www.clinicalresearchresources.com\/products\/book-3d-2026-common-terminology-criteria-for-adverse-events-ctcae","provider":"Clinical Research Resources, LLC","version":"1.0","type":"link"}